Publications

Lutey K, White PB, Cammon H, Trester M, Brumfield S, Neumeier JJ, Pincus S, Haushalter RW, Heinemann J. Multi-Component Analysis of Protein- and DNA-Coated Magnetic Nanoparticles Using Electrochemical Impedance Spectroscopy with Interdigitated Electrode Sensors. Bioengineering. 2025; 12(12):1334. https://doi.org/10.3390/bioengineering12121334

Chlebek C, McAndrews C, Aaronson B, Welhaven HD, Yu K, Costa SN, Shaver J, Silvia S, DeMambro VE, June RK, McGee-Lawrence ME, Rosen CJ. In C57BL/6J mice, weight loss in previously obese mice reduced bone mass and shifted the cortical bone metabolism. Bone. Vol 202, 2026, 117690, ISSN 8756-3282, https://doi.org/10.1016/j.bone.2025.117690.

*Schomberg-Sanchez IS, Robinson WC, Sanderson ME, Mosquera MA, Lemon CM. Hangman dipyrrin complexes. Chem Sci. 2025 Nov 3. doi: 10.1039/d5sc06893b. Epub ahead of print. PMID: 41229913; PMCID: PMC12603804.

*Singh S, Sorayah R, Chen Y, Mulholland CV, Daher W, Pee CJE, Casandra TAZ, Wee D, Oehlers SH, Kline KA, Chng SS, Berney M, Kremer L, Moraski G, Pethe K (2025 Oct) A bioluminescence-based chemical screen identifies a bactericidal naphthalene scaffold targeting MmpL3 in Mycobacterium abscessus. bioRxiv 2025.10.26.684512; https://doi.org/10.1101/2025.10.26.684512

Brahmachary PP, Erdogan AE, Myers EP, June RK. Metabolomic Profiling and Characterization of a Novel 3D Culture System for Studying Chondrocyte Mechanotransduction. Cel. Mol. Bioeng. (2025). https://doi.org/10.1007/s12195-025-00872-z

Gauvin CC, Tokmina-Lukaszewska M, Waghwani HK, McBee SC, Douglas T, Bothner B, Lawrence CM (2025 Oct 6). The Mechanism of Mineral Nucleation and Growth in a Mini-Ferritin. Journal of the American Chemical Society, (), . doi: 10.1021/jacs.5c05464. ID: 41052476.

Acharjee A, Ghiara G, Beech IB, Fields MW, Amendola R (Dec 2025). Mitigation of copper corrosion in the presence of an organic oxyanion through microstructural optimization. Corrosion Science, Volume 257,113358, ISSN 0010-938X. https://doi.org/10.1016/j.corsci.2025.113358.

Gurney SC, Cooper G, Bhattarai P, Schwarz B, Brandes N, Bothner B, Miles MP. FACSM¹. 30-minutes Of Aerobic Exercise Elicits A Decrease In Lipid Mediators: 1929. Medicine & Science in Sports & Exercise 57(10S):p 634, October 2025. | DOI: 10.1249/01.mss.0001160260.36188.70

*Kashyap R, Deere TM, Dhamad A, Chanderban M, Tokmina-Lukaszewska M, Bothner B, Lessner DJ, Antony E (2025 Sep 10). Cryo-EM structure of a methanogen nitrogenase-PII protein supercomplex. bioRxiv : the preprint server for biology, (), . . ID: 40964395.

Cooper G, Bhattarai P, Sather B, Bailey ML, Chamberlin M, Miles M, Bothner B (Sep 2025). Dietary Intervention with Cottonseed and Olive Oil Differentially Affect the Circulating Lipidome and Immunoregulatory Compounds—A Randomized Clinical Trial. Metabolites. 15(9):599. https://doi.org/10.3390/metabo15090599

Spears ML, Cooper G, Sather B, Peterson E, Boles JA, Bothner B, Miles MP (Sep 2025). Postprandial amino acids and health markers from organic grass-fed and conventional beef in healthy participants – a pilot randomized clinical trial. CyTA - Journal of Food, 23(1). https://doi.org/10.1080/19476337.2025.2554230

*Myers EP, Gallagher A, Welfley A, Battles S, Gregory A, Brahmachary P, Greenwood M, June RK (2025 Aug 6). Targeted analysis of chondrocyte central metabolites in response to cyclical compression and shear deformations. bioRxiv : the preprint server for biology, (), . . ID: 40799567.

Dieter EM, Larson J, Tokmina-Lukaszewska M, Xiong J, Green J, Guo Y, Broderick WE, Bothner B. Broderick JB (2025), Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding. FEBS Lett. https://doi.org/10.1002/1873-3468.70120

Deveryshetty J, Mistry A, Pangeni S. et al. Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination. Nat Commun 16, 6685 (2025). https://doi.org/10.1038/s41467-025-61811-0

Mattice JR, Shisler KA, Malone JR, Murray NA, Tokmina-Lukaszewska M, Nath AK, Flusche T, Mus F, DuBois JL, Peters JW, Bothner B (2025 June 20). Long-Range Allosteric Communication Modulated by Active Site Mn(II) Coordination Drives Catalysis in Xanthobacter autotrophicus Acetone Carboxylase. Int. J. Mol. Sci. 2025, 26(13), 5945; https://doi.org/10.3390/ijms26135945.

*Stauffer S, Welhaven H, Hislop B, Jones BA, Levi M, June RK, Heveran CM. Adenine-induced kidney disease alters the cortical bone metabolome of C57BL/6J mice in a manner that depends on sex. bioRxiv [Preprint]. 2025 Jun 3:2025.06.02.657438. doi: 10.1101/2025.06.02.657438. PMID: 40502128; PMCID: PMC12157587.

Bodle KB, Kirkland CM (June 2025).Environmentally-grown aerobic granular sludge performs more complete pharmaceutical biodegradation and wastewater treatment than lab-grown granules, International Biodeterioration & Biodegradation, Volume 202, 106081, ISSN 0964-8305, https://doi.org/10.1016/j.ibiod.2025.106081.

Brown K, Vahidi G, Hislop BD, Moody M, Watson S, Welhaven HD, Behzad R, Paton KO, Karim L, June RK, Martin SA, Heveran CM (2025 Jun 3). Short-term high-fat diet impacts bone material properties and metabolism for adult and aged C57BL/6JN mice. Communications biology, 8(1), 850. . ID: 40461602.

Trousdale RC, Tokmina-Lukaszewska M, Bothner B, Walker RA (2025 May 16). Perfluorooctanoic Acid Destabilizes Hemoglobin Structure at Submicromolar Concentrations. The journal of physical chemistry. B, (), . doi: 10.1021/acs.jpcb.5c01380. ID: 40378342.

Smolinski SL, Tokmina-Lukaszewska M, Holland JM, Guo Z, Kisgeropoulos E, Bothner B, King PW, Lubner CE (2025 May 14). Modulation of cyanobacterial Photosystem I protein environment and spectral capacity in response to changes in electron flow pathways and photon flux. The Journal of biological chemistry, (), 110233. doi: 10.1016/j.jbc.2025.110233. ID: 40378960.

Kashyap R, Walsh N, Deveryshetty J, Tokmina-Lukaszewska M, Zhao K, Gan YJ, Hoffman BM, Sarangi R, Bothner B, Bennett B, Antony E (2025 Apr 24). Cryo-EM captures the coordination of asymmetric electron transfer through a di-copper site in DPOR Nature Communications, 16(), 3866. . PMCID: 12022308.

Rodrigues da Silva R, Larson J, Bothner B, DuBois JL (2025 April 01). Heme and iron limitation in a GI-tract foundation species leads to a reshuffling of the metalloproteome and a shift toward manganese usage. Frontiers in chemistry, 13(), 1562189. . PMID: 40242659

Bergstrom AR, Glimm MG, Houske EA, Cooper G, Viles E, Chapman M, Bourekis K, Welhaven HD, Brahmachary PP, Hahn AK, June RK (2025 Mar). Metabolic Profiles of Encapsulated Chondrocytes Exposed to Short-Term Simulated Microgravity. Annals of biomedical engineering, 53(3), 785-797. . ID: 39695002.

Falvo CA, Crowley DE, Benson E, Hall MN, Schwarz B, Bohrnsen E, Ruiz-Aravena M, Hebner M, Ma W, Schountz T, Rynda-Apple A, Plowright RK (2025 Feb). Diet-induced changes in metabolism influence immune response and viral shedding in Jamaican fruit bats. Proceedings. Biological sciences, 292(2041), 20242482. . ID: 39968620.

*Welhaven HD, Welfley AH, Brahmachary PP, Smith DF, Bothner B, June RK (2025 Feb 7). Tissue-specific and spatially dependent metabolic signatures perturbed by injury in skeletally mature male and female mice. bioRxiv : the preprint server for biology, (), . . ID: 39975211.

Jackson OD, Reyes A, Stein CD, Larson NG, Andrews CT, Neufeldt SR (2025 Jan 29). C2-Selective Palladium-Catalyzed C-S Cross-Coupling of 2,4-Dihalopyrimidines. Journal of the American Chemical Society, 147(4), 3017-3022. . ID: 39829005.

Cooper G, North R, Hunt-Smith T, Larson J, Rennie M, Bailey ML, Scarlata S, Merzdorf CS, Bothner B (2025 Jan 26). Persistent Metabolic Changes Are Induced by 24 h Low-Dose Lead (Pb) Exposure in Zebrafish Embryos. International journal of molecular sciences, 26(3), . . ID: 39940818.

Larson J, Tokmina-Lukaszewska M, Malone J, Hasenoehrl EJ, Kelly W, Fang X, White A, Patterson A, Bothner B (2025 Jan 8). The Use of Dansyl Chloride to Probe Protein Structure and Dynamics. International journal of molecular sciences, 26(2), . . ID: 39859172.

Loveday EK, Welhaven H, Erdogan AE, Hain KS, Domanico LF, Chang CB, June RK, Taylor MP (2025). Starve a cold or feed a fever? Identifying cellular metabolic changes following infection and exposure to SARS-CoV-2. PloS one, 20(2), e0305065. . ID: 39937842.

Hager MS, Cook JP, Bothner B, Weaver DK (2025). Untargeted metabolomic and transcriptomic analysis in spring and durum wheat reveals potential mechanisms associated with the early stem solidness phenotype and resistance to wheat stem sawfly. Frontiers in plant science, 16(), 1497732. . ID: 40046948.

Welhaven HD, Welfley AH, Bothner B, Messier SP, Loeser RF, June RK (2024 Dec 20). The metabolome of male and female individuals with knee osteoarthritis is influenced by 18-months of weight loss intervention: the IDEA trial. BMC musculoskeletal disorders, 25(1), 1057. . ID: 39707277.

Kant R, Lee LS, Patterson A, Gibes N, Venkatakrishnan B, Zlotnick A, Bothner B (2024 Oct 23). Small Molecule Assembly Agonist Alters the Dynamics of Hepatitis B Virus Core Protein Dimer and Capsid. Journal of the American Chemical Society, 146(42), 28856-28865. . ID: 39382517.

Pincus SH, Cole FM, Ober K, Tokmina-Lukaszewska M, Marcotte T, Kovacs EW, Zhu T, Khasanov A, Copié V, Peters T (2024 Oct 22). Conjugation of anti-HIV gp41 monoclonal antibody to a drug capable of targeting resting lymphocytes produces an effective cytotoxic anti-HIV immunoconjugate. Journal of virology, 98(10), e0064724. . ID: 39283123.

Spears M, Cooper G, Sather B, Bailey M, Boles JA, Bothner B, Miles MP (2024 Oct 3). Comparative Impact of Organic Grass-Fed and Conventional Cattle-Feeding Systems on Beef and Human Postprandial Metabolomics-A Randomized Clinical Trial. Metabolites, 14(10), . . ID: 39452914.

Larson J, Sather B, Wang L, Westrum J, Tokmina-Lukaszewska M, Pauley J, Copié V, McDermott TR, Bothner B (2024 Sep 2). Metalloproteomics Reveals Multi-Level Stress Response in Escherichia coli When Exposed to Arsenite. International journal of molecular sciences, 25(17), . . ID: 39273475.

Welhaven HD, Welfley AH, Pershad P, Satalich J, O (2024 Sep). Metabolic phenotypes reflect patient sex and injury status: A cross-sectional analysis of human synovial fluid. Osteoarthritis and cartilage, 32(9), 1074-1083. . ID: 37716406.

Chamberlin ML, Peach JT, Wilson SMG, Miller ZT, Bothner B, Walk ST, Yeoman CJ, Miles MP (2024 Aug 30). Polyphenol-Rich Aronia melanocarpa Fruit Beneficially Impact Cholesterol, Glucose, and Serum and Gut Metabolites: A Randomized Clinical Trial. Foods (Basel, Switzerland), 13(17), . . ID: 39272533.

Larson J, Tokmina-Lukaszewska M, Payne D, Spietz RL, Fausset H, Alam MG, Brekke BK, Pauley J, Hasenoehrl EJ, Shepard EM, Boyd ES, Bothner B (2024 Aug 21). Impact of mineral and non-mineral sources of iron and sulfur on the metalloproteome of Methanosarcina barkeri. Applied and environmental microbiology, 90(8), e0051624. . ID: 39023267.

Costello SM, Schultz A, Smith D, Horan D, Chaverra M, Tripet B, George L, Bothner B, Lefcort F, Copié V (2024 Jul 31). Metabolic Deficits in the Retina of a Familial Dysautonomia Mouse Model. Metabolites, 14(8), . . ID: 39195519.

Kania MJ, Reyes A, Neufeldt SR (2024 Jul 17). Oxidative Addition of (Hetero)aryl (Pseudo)halides at Palladium(0): Origin and Significance of Divergent Mechanisms. Journal of the American Chemical Society, 146(28), 19249-19260. doi: 10.1021/jacs.4c04496. ID: 38959060.

Larson NG, Norman JP, Neufeldt SR (2024 May 3). Mechanistic Origin of Ligand Effects on Exhaustive Functionalization During Pd-Catalyzed Cross-Coupling of Dihaloarenes. ACS catalysis, 14(9), 7127-7135. . ID: 38911468.

Welhaven HD, Viles E, Starke J, Wallace C, Bothner B, June RK, Hahn AK (2024 Apr 9). Metabolomic profiles of cartilage and bone reflect tissue type, radiography-confirmed osteoarthritis, and spatial location within the joint. Biochemical and biophysical research communications, 703(), 149683. doi: 10.1016/j.bbrc.2024.149683. ID: 38373382.

Welhaven HD, Welfley AH, Brahmachary P, Bergstrom AR, Houske E, Glimm M, Bothner B, Hahn AK, June RK (2024 Mar 25). Metabolomic Profiles and Pathways in Osteoarthritic Human Cartilage: A Comparative Analysis with Healthy Cartilage. Metabolites, 14(4), . . ID: 38668311.

Joshi JR, Paudel D, Eddy E, Charkowski AO, Heuberger AL (2024). Plant necrotrophic bacterial disease resistance phenotypes, QTL, and metabolites identified through integrated genetic mapping and metabolomics in Solanum species. Frontiers in plant science, 15(), 1336513. . ID: 38504885.

Walls WG, Vagstad AL, Delridge T, Piel J, Broderick WE, Broderick JB (2024 Feb 28). Direct Detection of the α-Carbon Radical Intermediate Formed by OspD: Mechanistic Insights into Radical S-Adenosyl-l-methionine Peptide Epimerization. Journal of the American Chemical Society, 146(8), 5550-5559. . ID: 38364824.

Shisler KA, Kincannon WM, Mattice JR, Larson J, Valaydon-Pillay A, Mus F, Flusche T, Kumar Nath A, Stoian SA, Raugei S, Bothner B, DuBois JL, Peters JW (2024 Feb 14). Homologous acetone carboxylases select Fe(II) or Mn(II) as the catalytic cofactor. mBio, 15(2), e0298723. . ID: 38126751.

Fausset H, Spietz RL, Cox S, Cooper G, Spurzem S, Tokmina-Lukaszewska M, DuBois J, Broderick JB, Shepard EM, Boyd ES, Bothner B (2024 Feb 6). A shift between mineral and nonmineral sources of iron and sulfur causes proteome-wide changes in Methanosarcina barkeri. Microbiology spectrum, 12(2), e0041823. . ID: 38179920.

Bodle KB, Kirkland CM (2024 Feb). Pharmaceutical impacts on aerobic granular sludge morphology and potential implications for abiotic removal. Chemosphere, 350(), 141187. . ID: 38211794.

Hager MS, Hofland ML, Varella AC, Bothner B, Budak H, Weaver DK (2024). Untargeted metabolomics profiling of oat (Avena sativa L.) and wheat (Triticum aestivum L.) infested with wheat stem sawfly (Cephus cinctus Norton) reveals differences associated with plant defense and insect nutrition. Frontiers in plant science, 15(), 1327390. . ID: 38328705.

Deveryshetty, J., Chadda, R., Mattice, J.R. et al. Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes. Nat Commun 14, 6215 (2023). https://doi.org/10.1038/s41467-023-41993-1

Mikesell LD, Livinghouse T. Base-Catalyzed Phenol-Mannich Condensation of Preformed Cesium Iminodiacetate. The Direct Synthesis of Calcein Blue AM and Related Acyloxymethyl Esters. J. Org. Chem. 2023, 88, 16, 12064-12068. https://doi.org/10.1021/acs.joc.3c00155

Wilson SMG, Peach JT, Fausset H, Miller ZT, Walk ST, Yeoman CJ, Bothner B, Miles MP. Metabolic impact of polyphenol-rich aronia fruit juice mediated by inflammation status of gut microbiome donors in humanized mouse model. Frontiers in Nutrition. Vol 10, 2023. https://doi.org/10.3389/fnut.2023.1244692

Boyer NR, Tokmina-Lukaszewska M, Batista MB, Mus F, Dixon R, Bothner B, Peters JW. Structural insights into redox signal transduction mechanisms in the control of nitrogen fixation by the NifLA system. Proc. Natl. Acad. Sci. U.S.A. 120(30) e2302732120. https://doi.org/10.1073/pnas.2302732120

Alowaifeer AM, Wang Q, Bothner B, Sibert RJ, Joye SB, McDermott TR. Aerobic methane synthesis and dynamics in a river water environment. ALSO, Volumne 68, Issue 8, Pages 1762-1774. https://doi.org/10.1002/lno.12383

Houske EA,Glimm MG,Bergstrom AR,Slipher SK,Welhaven HD,Greenwood MC,Linse GM,June RK,Yu ASL,Wallace DP,Hahn AK. Metabolomic profiling to identify early urinary biomarkers and metabolic pathway alterations in autosomal dominant polycystic kidney disease. American Journal of Physiology-Renal Physiology,2023,324:6,F590-F602, https://doi.org/10.1152/ajprenal.00301.2022

Vahidi G, Moody M, Welhaven HD, Davidson L, Rezaee T, Behzad R, Karim L, Roggenbeck BA, Walk ST, Martin SA, June RK, Heveran CM, Germ‐Free C57BL/6 Mice Have Increased Bone Mass and Altered Matrix Properties but Not Decreased Bone Fracture Resistance, Journal of Bone and Mineral Research, Volume 38, Issue 8, 1 August 2023, Pages 1154–1174, https://doi.org/10.1002/jbmr.4835

Roshan, P., Kuppa, S., Mattice, J.R. et al. An Aurora B-RPA signaling axis secures chromosome segregation fidelity. Nat Commun 14, 3008 (2023). https://doi.org/10.1038/s41467-023-38711-2

Meslé MM, Gray CR, Dlakić M, DuBois JL.2023.Bacteroides thetaiotaomicron, a Model Gastrointestinal Tract Species, Prefers Heme as an Iron Source, Yields Protoporphyrin IX as a Product, and Acts as a Heme Reservoir. Microbiol Spectr,11:e04815-22. https://doi.org/10.1128/spectrum.04815-22

Steward, K.F., Refai, M., Dyer, W.E. et al. Acute stress reduces population-level metabolic and proteomic variation. BMC Bioinformatics 24, 87 (2023). https://doi.org/10.1186/s12859-023-05185-4

Larson J, Tokmina-Lukaszewska M, Fausset H, Spurzem S, Cox S, Cooper G, Copié V, Bothner B. Arsenic Exposure Causes Global Changes in the Metalloproteome of Escherichia coli. Microorganisms. 2023; 11(2):382. https://doi.org/10.3390/microorganisms11020382

Cheney AM, Costello SM, Pinkham NV, et al. Gut microbiome dysbiosis drives metabolic dysfunction in Familial dysautonomia. Nat Commun 14, 218 (2023). https://doi.org/10.1038/s41467-023-35787-8

Elliff J, Biswas A, Roshan P, Kuppa S, Patterson A, Mattice J, Chinnaraj M, Burd R, Walker SE, Pozzi N, Antony E, Bothner B, Origanti S. Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit, Nucleic Acids Research, Volume 51, Issue 4, 28 February 2023, Pages 1803–1822, https://doi.org/10.1093/nar/gkac1266

Lemon CM, Powers DC, Huynh M, Maher AG, Phillips AA, Tripet BP, Nocera DG. Ag(III)···Ag(III) Argentophilic Interaction in a Cofacial Corrole Dyad. Inorg. Chem. 2023, 62, 1, 3-17. https://doi.org/10.1021/acs.inorgchem.2c02285 

Brahmachary, P.P., Welhaven, H.D., June, R.K. (2023). Metabolomic Profiling to Understand Chondrocyte Metabolism. In: Stoddart, M.J., Della Bella, E., Armiento, A.R. (eds) Cartilage Tissue Engineering. Methods in Molecular Biology, vol 2598. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-2839-3_11 

Bodle, K.B., Pernat, M.R. & Kirkland, C.M. Pharmaceutical Sorption to Lab Materials May Overestimate Rates of Removal in Lab-Scale Bioreactors. Water Air Soil Pollut 233, 505 (2022). https://doi.org/10.1007/s11270-022-05974-2 

Kempa J, O’Shea-Stone G, Moss CE, Peters T, Marcotte TK, Tripet B, Eilers B, Bothner B, Copié V, Pincus SH. Distinct Metabolic States Are Observed in Hypoglycemia Induced in Mice by Ricin Toxin or by Fasting. Toxins. 2022; 14(12):815. https://doi.org/10.3390/toxins14120815 

Peach, J.T., Mueller, R.C., Skorupa, D.J. et al. Longitudinal analysis of the Five Sisters hot springs in Yellowstone National Park reveals a dynamic thermoalkaline environment. Sci Rep 12, 18707 (2022). https://doi.org/10.1038/s41598-022-22047-w 

Angela Patterson, Aidan White, Elizabeth Waymire, Sophie Fleck, Sarah Golden, Royce A Wilkinson, Blake Wiedenheft, Brian Bothner, Anti-CRISPR proteins function through thermodynamic tuning and allosteric regulation of CRISPR RNA-guided surveillance complex, Nucleic Acids Research, Volume 50, Issue 19, 28 October 2022, Pages 11243–11254, https://doi.org/10.1093/nar/gkac841 

Hislop BD, Devine C, June RK, Heveran CM. Subchondral bone structure and synovial fluid metabolism are altered in injured and contralateral limbs 7 days after non-invasive joint injury in skeletally-mature C57BL/6 mice. Osteoarthritis and Cartilage. 2022, Vol 30, Issue 12, Pgs 1593-1605. https://doi.org/10.1016/j.joca.2022.09.002 

Kuppa, S., Deveryshetty, J., Chadda, R. et al. Rtt105 regulates RPA function by configurationally stapling the flexible domains. Nat Commun 13, 5152 (2022). https://doi.org/10.1038/s41467-022-32860-6 

Liu R, Marshall K, Ma R, et al. Syntheses and studies of deuterated Imdiazo[1,2-a]pyridine-3-carboxamides with potent anti-tuberculosis activity and improved metabolic properties. Bioorg Chem. 2022;128:106074. doi:10.1016/j.bioorg.2022.106074 

Frabitore C, Lépeule J, Livinghouse T. Copper(I)-Catalyzed Cross-Coupling of 1-Bromoalkynes with N-Heterocyclic Organozinc Reagents. Molecules. 2022; 27(14):4561. https://doi.org/10.3390/molecules27144561 

Hope D. Welhaven, Ghazal Vahidi, Seth T. Walk, Brian Bothner, Stephen A. Martin, Chelsea M. Heveran, Ronald K. June, The Cortical Bone Metabolome of C57BL/6J Mice Is Sexually Dimorphic, JBMR Plus, Volume 6, Issue 7, 1 July 2022, e10654, https://doi.org/10.1002/jbm4.10654 

Pagnier A, Balci B, Shepard EM, Yang H, Warui DM, Impano S, Booker SJ, Hoffman BM, Broderick WE, Broderick JB. [FeFe]-Hydrogenase: Defined Lysate-Free Maturation Reveals a Key Role for Lipoyl-H-Protein in DTMA Ligand Biosynthesis. Angewandte Chemie. Vol 61, Issue 22, 2022, e202203413, https://doi.org/10.1002/anie.202203413 

Fredrikson JP, Brahmachary PP, Erdoğan AE, Archambault ZK, Wilking JN, June RK, Chang CB. Metabolomic Profiling and Mechanotransduction of Single Chondrocytes Encapsulated in Alginate Microgels. Cells. 2022; 11(5):900. https://doi.org/10.3390/cells11050900 

June RK, Steward KF, Welhaven HD, Katzman SA, Yik JH, Haudenschild DR. Correlations between metabolites in the synovial fluid and the serum: An equine study. Osteoarthritis and Cartilage, Vol 30, Supplement 1, 2022, Page S128. 

Wallace CW, Hislop B, Hahn AK, Erdogan AE, Brahmachary PP, June RK. Correlations between metabolites in the synovial fluid and serum: A mouse injury study. Journal of Orthopaedic Research, Vol 40, Issue 12, Pgs 2792-2802, https://doi.org/10.1002/jor.25310 

Lundahl MN, Sarksian R, Yang H, Jodts RJ, Pagnier A, Smith DF, Mosquera MA, van der Donk WA, Hoffman BM, Broderick WE, Broderick JB. Mechanism of Radical S-Adenosyl-L-methionine Adenosylation: Radical Intermediates and teh Catalytic Competence of the 5’-Deoxyadenosyl Radical. J. Am. Chem. Soc. 2022, 144, 11, 5087-5098. https://doi.org/10.1021/jacs.1c13706 

W.M. Kincannon, M. Zahn, R. Clare, J. Lusty Beech, A. Romberg, J. Larson, B. Bothner, G.T. Beckham, J.E. McGeehan, & J.L. DuBois,Biochemical and structural characterization of an aromatic ring–hydroxylating dioxygenase for terephthalic acid catabolism, Proc. Natl. Acad. Sci. U.S.A. 119 (13) e2121426119, https://doi.org/10.1073/pnas.2121426119 (2022). 

Mattice JR, Shisler KA, DuBois JL, Peters JW, Bothner B. A catalytic dyad modulates conformational change in the CO2-fixing flavoenzyme 2-ketopropyl coenzyme Moxidoreductase/ carboxylase. Journal of Biological Chemistry. Vol 298, Issue 5, 2022, 101884. https://doi.org/10.1016/j.jbc.2022.101884 

Stewart PS, Williamson KS, Boegli L, Hamerly T, White B, Scott L, Hu X, Mumey BM, Franklin MJ, Bothner B, Vital-Lopez FG, Wallqvist A, James GA. 2022. Search for a Shared Genetic or Biochemical Basis for Biofilm Tolerance to Antibiotics across Bacterial Species. Antimicrob Agents Chemother 66:e00021-22. https://doi.org/10.1128/aac.00021-22 

Welhaven HD, McCutchen CN, June RK. Effects of mechanical stimulation on metabolomic profiles of SW1353 chondrocytes: shear and compression. Biol Open (2022) 11 (1):bio058895. https://doi.org/10.1242/bio.058895 

Meslé MM, Mueller RC, Peach J, Eilers B, Tripet BP, Bothner B, Copié V, Peyton BM (2022). Isolation and Characterization of Lignocellulose-Degrading Geobacillus thermoleovorans from Yellowstone National Park. Appl Environ. Microbiol. 88:e00958-21. https://doi.org/10.1128/AEM.00958-21